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How to Set Up Your ResMed AirMini

Hands placing a ResMed AirMini travel CPAP machine into a black quilted travel bag
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If you just got your AirMini, you are probably excited to use it right away. But if you feel overwhelmed by the setup, tubing, masks, HumidX adapters, etc., you are not alone.

This walkthrough covers every part of the process: which setup pack goes with which mask, how to connect the tubing, how to install HumidX for waterless humidification, how to pair the app, and how to reach the clinical menu that most AirMini users never find. By the end of this guide, your machine will be configured, your mask sealed, and you will be ready for tonight.

AirMini setup starts with choosing the right setup pack for your mask. Firmly connect the gray end of the AirMini tubing to the machine's air outlet. If you want waterless humidification, install a HumidX cartridge in the connector before attaching it to the mask. Plug in the power, fit the mask, and pair the AirMini app via Bluetooth to track your data and access settings.

"If you just got your AirMini, you're probably excited to use it right away. But if you're feeling overwhelmed by the setup with things like tubing, the masks, HumidX adapters, etc., you're not alone."

Gabriel, CPAP Specialist, Sleeplay

The sections below walk through every part of the setup in order, from the parts you need on day one to a first-trip checklist.

What You Need to Set Up the AirMini

The ResMed AirMini AutoSet Travel CPAP Machine fits in your hand, but it requires a few specific components to deliver therapy. Most of these are sold separately from the device. The AirMini AutoSet is $919 at Sleeplay (price checked September 25, 2026; a prescription is required).

Still deciding? Our ResMed AirMini review covers who it suits, and AirMini vs Transcend Micro compares it with its closest rival.

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Here is what you need on day one:

One important detail: the AirMini does NOT include a mask or tubing out of the box. The setup pack is sold separately for most masks. The P10 and N30 packs are the exception and include the mask. The N20, F20, and F30 packs do not. Sleeplay carries all AirMini supplies and essential CPAP equipment.

"When you take it out of the box you're going to be having your manual, your actual device, your power cord, and a travel bag."

Oswald 'Ozzy' Azua, Respiratory Therapist, Sleeplay

Which Masks Work with the AirMini

Seven ResMed masks are officially compatible with the AirMini: AirFit P10 for AirMini, AirFit N30 for AirMini, AirFit N20, AirTouch N20, AirFit F20, AirTouch F20, and AirFit F30. [2] Each requires its own setup pack, which includes the connector and tubing designed for that mask. The table below lists all seven, with a direct link to each setup pack (prices checked September 25, 2026).

ResMed mask Type HumidX compatible Mask in pack Setup pack at Sleeplay Price
AirFit N20 Nasal Yes (HumidX and HumidX Plus included) No N20 Setup Pack $62
AirTouch N20 Nasal (memory foam cushion) Yes (HumidX and HumidX Plus included) Yes AirTouch N20 with AirMini Setup Pack $170
AirFit N30 Nasal cradle Yes Yes N30 Setup Pack $165
AirFit P10 Nasal pillow Yes Yes P10 Setup Pack $165
AirFit F20 Full face Yes (HumidX F20 cartridge) No F20 Setup Pack $56
AirTouch F20 Full face Yes (HumidX F20 cartridge) No F20 Setup Pack $56
AirFit F30 Full face No No F20/F30 Setup Pack (F30 version out of stock on September 25, 2026) $56

Sources: mask list [2]; HumidX with N20, N30, and P10 and HumidX F20 with the F20 series [3]; "Waterless humidification is not available for AirFit F30" (ResMed product page footnote) [2]; pack contents and prices from the Sleeplay product listings, checked September 25, 2026.

If you want the mask and the pack in one box, Sleeplay also sells the AirFit F20 with AirMini Setup Pack ($211), the AirTouch F20 with AirMini Setup Pack ($215), and the AirFit N20 with AirMini Setup Pack ($139.99), prices checked September 25, 2026.

One thing worth mentioning about the AirFit F30: it is NOT compatible with HumidX. If you use an F30 and want humidification, you'll need to switch to a different mask. Still deciding which mask to get? Our CPAP mask guide compares nasal, pillow, and full-face options side by side so you can find the right fit before committing to a setup pack.

If you are torn between nasal and full-face, the American Academy of Sleep Medicine's review found that nasal interfaces had better adherence than oronasal (full-face) masks, so a nasal or pillow setup is worth trying first if you breathe through your nose. [4]

"once you have the elbow connected to the F20 and only when the elbow is connected to the F20 can you take this here with the blue side on the inside ..."
"you cannot use that with the F30 okay it's good for the F20 okay but it's not good with the F30 it won't fit"

James Curles, Sleep Coach, Sleeplay

How to Set Up the AirMini with a Compatible Mask

Once you have the right setup pack, assembly is quick. Here is the full process, step by step.

  1. Confirm your setup pack matches your mask. Each pack is built for one mask family (N20, N30, P10, or F20/F30). The wrong pack leaves a connector that will not seat properly.
  2. Connect the gray end of the AirMini tubing firmly to the machine's air outlet. [1] To remove it later, press the side buttons on the cuff and pull it away.
  3. Install HumidX in the connector if you are using it. Twist the connector open, hold the HumidX at the sides with the colored side pointing down, insert it, then push the connector together and twist until it locks. [1] The HumidX section below covers the full process.
  4. Attach the connector to your mask. Seat it firmly with no gaps between the connector and the mask port.
  5. Plug in the power supply.
  6. Fit the mask and adjust for a good seal.
  7. Press Start, or just breathe normally if SmartStart is on. SmartStart detects your breathing and starts therapy automatically, so you don't need to press a button. [1]

If air hisses at the machine end or the mask end, the system is usually assembled incorrectly. ResMed's first fix for leaks and noise is to check that every part is connected as described in its setup steps [1]; reseat the tubing cuff and the connector before you change anything else.

*Change every 3-6 Months
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How to Set Up the AirMini with Your Own (Non-Compatible) Mask

If your preferred mask is not on the AirMini compatibility list, two adapter routes let you keep using it.

  • A universal mask adapter: Connects the AirMini to universal tubing that runs to almost any standard mask, as Gabriel demonstrates in the setup video. The compact setup stays intact while opening up a much wider range of mask options.
  • An AirMini tubing adapter: Lets you keep your AirMini tubing and connect it to your preferred mask. Slightly bulkier, but compatible with virtually any mask you already own.

The Snugell AirMini Hose Adapter is a popular third-party option that does the same job ($19.95, price checked September 25, 2026). It also supports a vCOM attachment, which softens airflow and noticeably reduces noise, a useful bonus on a travel machine.

One trade-off to be clear about: custom adapter setups mean you lose HumidX support. The HumidX cartridge lives in the mask-specific connector, which adapters bypass. You can still add waterless humidification with an inline heat and moisture exchanger (HME) between the tubing and your mask, the way Gabriel shows in the setup video.

Sleeplay carries the Breas HME ($6.50 each; price checked September 25, 2026); Breas says to discard it after 7 days, and it doesn't fit the AirMini setup pack or short-tube masks like the AirFit P10 and AirFit N20 (Breas instructions on the Sleeplay listing). You also add one or two extra connection points, each of which can leak air if anything isn't fully seated. If noise reduction in a custom setup is a priority, the Snugell AirMini Pro Hose Connector ($20.99) offers a bit more flexibility and a vCOM port.

"purchase a snuggle adapter lock it into place and then [ta-]da you're good to go with your Fisher [& Paykel] Solo now this snuggle adapter also enables you to connect a vCOM and vCOM softens the air flow it makes therapy easier but with travel [CPAP] machines it also reduces the noise"

Nick (Uncle Nicko), CPAP Reviews

How to Add Waterless Humidification with HumidX

Every AirMini user eventually asks how to humidify without carrying a water tank. HumidX is the answer.

HumidX is a small disposable capsule that sits inside the mask-side connector. It works as a Heat and Moisture Exchanger (HME): it captures moisture from your exhale and releases it back on your inhale. No water tank, no distilled water to pack, and nothing to spill in your bag. ResMed designed it to deliver performance similar to a ResMed AirSense 10 humidifier set between 2 and 5, with an unheated tube. [5]

Sleeplay offers two versions: HumidX Standard covers most environments for everyday home or travel use, while HumidX Plus is built for dry climates, high altitudes, and the low-humidity air you find in airplane cabins. [1] Both are $37 for a 3-pack and $62 for a 6-pack (price checked September 25, 2026).

The AirFit F20 and AirTouch F20 use a separate cartridge (HumidX for AirFit/AirTouch F20) with a form factor specific to the F20 connector ($44 for a 3-pack; price checked September 25, 2026). Do not substitute a standard HumidX cartridge.

Installing HumidX

  1. Open the connector by gently twisting it.
  2. Hold the HumidX at the sides, with the colored side pointing down toward the tube, and insert it. [1]
  3. Push the connector back together and twist until it locks in place, then attach it to your mask.

Replace HumidX every 30 days from when you open the package, regardless of how many nights you use it. [1] If you only use the AirMini a few nights a week, one cartridge still covers the full month.

Some forum tips say to soak the HumidX before use. Do not: ResMed says the HumidX should be dry when you start therapy. [1] If water droplets form on your nose, mask, or tubing, switch from HumidX Plus to HumidX Standard, or from HumidX to none.

Using the AirMini without HumidX is completely fine. Some users prefer it. Therapy air will feel drier without it, especially during air travel or in low-humidity environments: in a sleep-lab study, CPAP without humidification lowered the relative humidity of the air people breathed from 80% to 63% with their mouths closed and to 39% with their mouths open. [6] If that becomes uncomfortable, adding HumidX Standard is an easy fix. In notably dry conditions, HumidX Plus delivers more moisture.

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"This mimics a hum[idifier] experience without a water tank needed. It captures moisture from your exhale and reuses it on your inhale. It's not exactly like a heated humidifier, but for travel or everyday comfort, it works beautifully."

Gabriel, CPAP Specialist, Sleeplay

How Do You Pair the AirMini with the App?

To pair the ResMed AirMini, download the AirMini app, turn on Bluetooth, and press the Bluetooth button on the machine until its light flashes blue. Tap Connect, choose your AirMini, then enter the four-digit key on the back of the machine or tap Scan code to read the QR code.

The AirMini has no screen, so the app holds all your data and settings. Without pairing it, you can't see how your therapy is going or make any adjustments. To set up the AirMini app, follow these steps:

  1. Download the AirMini app from the iOS App Store or Google Play.
  2. Enable Bluetooth on your phone, then open the app and accept the consents it asks for on first launch.
  3. Press the Bluetooth button on the AirMini when the app prompts you. The light flashes blue when the machine is ready to pair. [1]
  4. Tap Connect, then select your AirMini from the list.
  5. Enter the four-digit key located on the back of the AirMini, or tap Scan code and point your camera at the QR code, which is also on the back. [1] Tap Done. A Bluetooth icon in the top right of the app confirms the connection.

Once paired, the dashboard shows a daily score out of 100: usage hours are worth up to 70 points (one hour earns 10, six hours earn 60), mask seal up to 20, events per hour up to 5, and mask on/off up to 5, with the last 30 days saved. [3] It works like the score AirSense users see; our guide to reading your myAir score explains each part.

Your phone doesn't need to be connected to sleep: the Start/Stop button starts therapy without Bluetooth, and the app is only needed for data and comfort settings. [7] The AirMini pairs with one phone at a time [8], within about 6 to 9 meters. [9]

Before your first night: run Test Drive and Mask Fit

Run the AirMini app's two guided checks before your first night.

  • Test Drive: In the More menu, tap Start air. The AirMini starts at 4 cmH2O, then you step it up to 7 and finally to 10 cmH2O, with a 3-minute limit. [3] It is a rehearsal, not your prescribed setting.
  • Mask Fit: On the Sleep screen, tap Mask Fit, then START Mask Fit, and adjust the cushion and headgear until the app shows a Good mask seal. [3] Mask Fit only runs from the app on a smartphone or compatible smart device.

Why it matters: In new CPAP users, more than 4 hours of use a night by night three predicted who was still using CPAP a month later. [10] Our guide to your first 30 days on CPAP covers what comes next.

How to Adjust Pressure and Access the Clinical Menu

The AirMini app lets you manage therapy by adjusting comfort settings yourself on the Sleep screen (Therapy, then Options): Ramp Time (gradually increases pressure as you fall asleep), Pressure Relief, also called EPR (softens the exhale, once your provider has enabled it), SmartStart (begins therapy when you breathe into the mask), and SmartStop (stops it when you take the mask off). [3]

Pressure settings live in a hidden part of the app called the clinical menu, also referred to as clinical settings, clinical home, or clinical mode. You access the clinical menu with a specific gesture inside the app.

How do you open the AirMini clinical menu?

To open the AirMini clinical menu, open the AirMini app and tap the Bluetooth icon in the top-right corner of the dashboard. On the Bluetooth pairing screen, press and hold the ResMed logo and the AirMini logo at the same time, one finger on each, for at least three seconds to open the clinical menu.

  1. Open the AirMini app.
  2. Tap the Bluetooth symbol in the top right to enter the device view.
  3. Two logos appear on that screen: ResMed and AirMini. Place one finger on each logo and hold both down for at least 3 seconds. [11]
  4. The clinical home settings will open.
  5. To leave, tap < Exit in the Navigation tab. [12]

If the two logos do not appear: ResMed documents two places where the gesture works: the Bluetooth pairing screen described above and the app's home page. [12] If one does not respond, try the other.

Check that your provider's change took effect. ResMed provides two confirmations: a message in the app and the light above the power button on the AirMini flashing three times, alternating white and green. You can also see the updated values on the Machine settings or Sleep screen. [11]

From there, you will see the current therapy mode and pressure range. The AirMini runs between 4 and 20 cmH2O in every mode. [1] Three modes are available:

  • AutoSet mode: The machine reads your breathing patterns and adjusts pressure throughout the night within your prescribed range.
  • CPAP mode: The machine delivers a single fixed pressure level throughout the night, regardless of breathing patterns.
  • AutoSet for Her: ResMed's AutoSet mode for female patients with mild to moderate obstructive sleep apnea. [1]

In both AutoSet modes, you set a minimum and maximum pressure instead of a single number, and the machine adjusts between them. CPAP mode uses a single fixed value.

Neither mode is stronger by default. The American Academy of Sleep Medicine's review found no clinically significant difference in outcomes between auto-adjusting and fixed CPAP, so the mode is part of your prescription rather than a preference setting. [4]

What each setting in the clinical menu actually does

Setting Values Who changes it What it changes
Therapy mode CPAP, AutoSet, AutoSet for Her Your provider (clinical menu) Fixed pressure, or a range the machine moves within
Pressure 4 to 20 cmH2O Your provider (clinical menu) The air pressure delivered. Your prescribed value comes from your provider
Ramp Time Off, 5 to 45 minutes, or Auto You (Sleep, Therapy, Options) Starts lower and builds up while you fall asleep; Auto waits until it detects you are asleep
Pressure Relief (EPR) On or Off once enabled Enabled by your provider, then you can switch it Drops pressure slightly when you exhale
SmartStart / SmartStop On or Off You (Sleep, Therapy, Options) Starts therapy when you breathe in, stops it a few seconds after you take the mask off

Sources: ResMed AirMini User Guide (modes, 4 to 20 cmH2O, SmartStop) [1]; ResMed AirMini app Patient eHelp (Ramp values, Pressure Relief, where each setting lives) [3]. Ramp Time cannot be changed once a session has started; stop therapy first.

Your provider prescribes your pressure. Use this menu to see what your machine is set to and to understand what each setting means, not to prescribe yourself a new one.

Always consult your sleep specialist before changing pressure settings. The clinical menu is protected for a reason. Adjusting pressure outside your prescribed range can reduce therapy effectiveness or cause discomfort. If you are unsure whether your pressure is right, our guide to signs your CPAP pressure is too high covers what to tell your provider.

"Once paired, go to the My AirMini dashboard in the app. Tap the Bluetooth symbol on the top right, which will take you to your machine. Then, with two fingers, hold down the logo, which will take you to the [clinical] home settings. Here you'll see the pressure mode either AutoSet, which auto adjusts during the night, or CPAP mode, which gives you a fixed pressure. ..."
"Important note, always consult with your sleep specialist or doctor before making major pressure changes."

Gabriel, CPAP Specialist, Sleeplay

How to Make Your AirMini Quieter

The AirMini is slightly louder than a full-size ResMed machine: ResMed measures it about 2 dBA louder than the AirSense 10, within a measurement uncertainty of plus or minus 2 dBA [13], and its motor is 45% smaller than the AirSense 10's [14]. Nick (Uncle Nicko) of CPAP Reviews puts the trade-off in plain words: 'because of the small size there's not much room for sound abatement foam', and he adds that 'most patients who use this device find the noises very acceptable'. Two things help if it is bothering you.

  1. Choose a quieter mask: With a mask attached, ResMed rates the N20 and P10 connectors at 15 dBA versus 19 dBA for the F20 connector [1], so a nasal or pillow setup such as the AirFit P10 tends to run quieter than full face. Mask seal quality matters here, too. A well-fitted mask leaks less air, and less leakage means less noise.
  2. Add a CPAP muffler on custom setups: If you are using a non-compatible mask with an adapter, connecting a CPAP muffler such as the Breas Q-Lite CPAP Muffler ($31.85, price checked September 25, 2026) between the adapter and the tube can noticeably reduce the sound coming from the machine. The Snugell AirMini Pro Hose Connector makes this easy by supporting a vCOM attachment.

For every other fix, from mask leaks to where you set the machine, see our full guide on how to reduce CPAP noise.

"If the AirMini feels a little noisy to you, especially with a custom setup, check this out. You can use a [Q-Lite] CPAP muffler like this. Take your AirMini and connect it to the adapter, which then connects to the [Q-Lite] muffler. Then connect it to a generic tube and finally your own CPAP mask. This helps dampen the sound of your machine and make your sleep more peaceful."

Gabriel, CPAP Specialist, Sleeplay

How Often Should You Replace AirMini Parts?

ResMed recommends replacing the AirMini air filter and tubing at least every six months, the N20 and F20 connectors at least every six months, and each HumidX within 30 days of opening. The AirMini app will not remind you when parts are due, so keep your own schedule.

Part How to care for it Replace Shop
Air filter Cannot be washed; check it for holes or dust blockage At least every 6 months, sooner if damaged ResMed AirMini standard filters (2-pack $8), AirMini fine filters
AirMini tubing Wash weekly in warm water with a mild liquid detergent; no dishwasher; dry out of direct sun At least every 6 months AirMini tubing ($37)
N20 or F20 connector Clean daily with warm water, mild liquid detergent, and a soft brush on the vent holes At least every 6 months N20 connector, F20 connector ($19 each)
HumidX, HumidX Plus Inspect daily; cannot be washed; store dry Within 30 days of opening HumidX Standard, HumidX Plus
Machine Wipe the outside weekly with a dry cloth; keep the filter cover on Design life 5 years; 2-year ResMed warranty Filter cover ($9.95)

Source: cleaning and technical specifications sections of the ResMed AirMini User Guide [1]; prices checked September 25, 2026. The app does not send replacement reminders. [15]

To change the filter: Slide off the filter cover, swap the filter, and slide the cover back on; keep the cover on at all times. [1] Skip bleach, alcohol, and scented or antibacterial soaps. [1] See our how to clean your CPAP guide, and our guide on cleaning a CPAP hose.

"for ResMed you want to change that filter at least once every six months I will tell you that you should check your filter after every time that you use the machine ..."
"if you go on a week vacation you take your machine and use it for a week after that week you do want to open up clean everything"

Oswald 'Ozzy' Azua, Respiratory Therapist, Sleeplay

If you want the three most common replacements in one box, the ResMed AirMini Essential Parts Bundle ($82, price checked September 25, 2026) includes three HumidX Plus cartridges, a standard 6-foot AirMini tube and a 2-pack of filters; see all CPAP filters.

What Should Be on Your AirMini First-Trip Checklist?

Before your first trip with the ResMed AirMini, pack the power supply, a plug adapter, spare HumidX cartridges, a filter, and ResMed's FAA compliance letter. Update the app and firmware at home, learn airplane mode, and plan power: the AirMini has no battery, so you need an outlet, a DC converter, or a compatible battery.

ResMed lists the AirMini at 10.6 oz (300 g). [1] Next to a ResMed AirSense 11 on camera, Nick (Uncle Nicko) of CPAP Reviews measured it 74% lighter and 72% smaller, and the full kit with tubing, power supply, and mask still 40% lighter and 33% smaller (Nick (Uncle Nicko) on the Sleeplay channel).

Pack or do this Why it matters Source
The 20 W power supply, plus a plug adapter for your destination The AirMini takes 100 to 240 V at 50 to 60 Hz, so it works on most power grids, but the plug shape still changes by country [User guide]
A spare 20 W power supply ($59), optional There is no internal battery; if the power supply is lost, therapy stops [ResMed product page]
The AirMini DC converter ($89) for car, RV or boat ResMed's 65 W DC/DC converter runs the AirMini from a 12 V or 24 V socket in a vehicle with a suitable battery [ResMed product page]
Spare HumidX cartridges (HumidX Plus for flights and high altitude) ResMed recommends HumidX Plus when the air is very dry, for example at high altitude or on an aircraft [User guide]
Spare filter and the Essential Parts Bundle ($82) for longer trips The filter cannot be washed, and the app will not remind you when parts are due [User guide]
ResMed's travel compliance letter (printed) It lists the AirMini AutoSet as meeting FAA requirements (RTCA/DO-160G, Section 21, Category M) [ResMed letter, March 17, 2026]
Update the AirMini app and firmware at home A postponed firmware update blocks your sleep data and comfort settings until it installs, and it needs internet [App eHelp]
Know your destination's altitude The AirMini is rated to operate from sea level to 8,500 ft (2,591 m) [User guide]
A case: AirMini Premium Travel Bag ($62) or ResMed travel case ($27) Keeps the machine, tubing and mask together and protected Sleeplay listings

Prices checked September 25, 2026.

Power off the grid: with no outlet, the AirMini runs from an external CPAP battery and an AirMini cable, such as the AirMini cable for the Medistrom Pilot-24 ($19.99). Battery picks live in our best CPAP batteries guide, and tent and RV setups in camping with a CPAP. Never lower your pressure to stretch a battery; it is prescribed.

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How to use airplane mode on the AirMini

  1. With the AirMini plugged in, press and hold the Bluetooth button for at least ten seconds, until the light turns white. [1]
  2. Do not use the AirMini app on the plane; start and stop therapy with the Start/Stop button on the machine. [1]
  3. While in airplane mode, the AirMini does not send data to the app [17]; your nights sync after you reconnect.
  4. To turn airplane mode off, press the Bluetooth button again; if the light stays white, hold it for at least 3 seconds until it flashes blue. [3]

Before you book: ResMed suggests calling your airline at least two weeks ahead, asking for a seat near power, and carrying a doctor's letter with the FAA letter. [18] The power supply is rated for aircraft power (115 V, 400 Hz). [1]

Does the AirMini count as a carry-on?

On airlines covered by the U.S. rule 14 CFR 382.121(b), an assistive device like the ResMed AirMini doesn't count toward your carry-on limit. Outside that rule, policies vary: the AirMini user guide says some airlines exclude medical devices and asks you to check with your airline before you fly.

Source What it says Applies to
14 CFR 382.121(b) [19] 'In implementing your carry-on baggage policies, you must not count assistive devices ... toward a limit on carry-on baggage.' Airlines covered by the U.S. Department of Transportation rule
ResMed AirMini User Guide [1] 'For some airlines, medical devices do not count toward carry-on luggage limits. Please check with your airline for their policy regarding medical equipment.' Any airline, worldwide

Quotes verified September 25, 2026. ResMed's compliance letter describes its CPAP machines as 'respiratory assistive devices' [16].

Pack the AirMini in its own case, carry it into the cabin, and expect TSA to ask you to take it out of the case for X-ray screening, like a laptop. TSA lists CPAP machines as allowed in carry-on bags with special screening instructions [20]; our guide to flying with a CPAP machine walks through screening, distilled water, and in-flight use step by step.

After the trip, clean everything when you get home. As Ozzy puts it in the replacement section above, after a week away, "you do want to open up and clean everything."

"Pack smart. Don't be that person digging through their bag at the airport for your power cords and cables."

Daniel Feldman, Sleeplay

Frequently Asked Questions

How do I get to the clinical menu on the AirMini?

Open the AirMini app and tap the Bluetooth symbol in the top right to reach the device screen. Two logos appear: ResMed and AirMini. Place one finger on each and hold for at least 3 seconds. If they don't respond, ResMed says the same gesture also works on the app's home page.

How do I change the pressure on my AirMini?

Pressure lives in the clinical menu, not on the main dashboard. Your provider sets a fixed pressure in CPAP mode or a minimum and maximum in the AutoSet modes. After you make a change, the app shows a confirmation, and the AirMini light flashes white and green three times.

What pressure range does the AirMini support?

The AirMini delivers between 4 and 20 cmH2O in every therapy mode: CPAP, AutoSet, and AutoSet for Her. This is the range published in the ResMed AirMini user guide. Your prescribed value within that range comes from your provider.

Can I adjust my CPAP settings myself?

You can open the clinical menu and see how your machine is configured. Your pressure is prescribed, so make changes with your sleep specialist. Use the menu to understand what each setting does, not to prescribe yourself a new pressure.

What therapy modes does the AirMini have?

Three: CPAP, which holds one fixed pressure all night; AutoSet, which adjusts within your prescribed range as you breathe; and AutoSet for Her, ResMed's AutoSet mode for women with mild to moderate obstructive sleep apnea.

What does EPR do and how do I change it?

EPR, which ResMed calls Pressure Relief, lowers pressure slightly when you exhale so breathing feels more natural. Your provider must enable it first; then you can turn it on or off in the app under Sleep > Therapy > Options.

How long can I set the ramp on the AirMini?

Ramp Time can be Off, anywhere from 5 to 45 minutes, or Auto. Ramp starts you at a lower pressure and builds up to your prescribed level while you fall asleep; in Auto, the AirMini waits until it detects you are asleep.

Can I use the AirMini without a HumidX?

Yes. The HumidX is optional waterless humidification. Without it the AirMini still delivers full therapy, though the air will feel drier. Many users skip it in humid climates and add it for flights or high altitude.

How do I install the HumidX?

Gently twist the connector open, hold the HumidX by its sides with the colored side down, and insert it dry, never soaked. Twist the connector closed until it locks. Replace it within 30 days of opening the pack.

How do I turn on airplane mode on the AirMini?

With the AirMini plugged in, press and hold the Bluetooth button for at least ten seconds until the light turns white. Do not use the app during the flight; start therapy with the Start/Stop button. Press the Bluetooth button again to exit.

References

  1. ResMed. AirMini User Guide (AMER, English): setup, HumidX, pairing, airplane mode, specifications, cleaning and replacement. https://document.resmed.com/documents/products/machine/airmini/user-guide/airmini_user-guide_amer_eng.pdf
  2. ResMed. AirMini travel CPAP product page (US): seven compatible masks, no internal battery, DC/DC converter, HumidX options. https://www.resmed.com/en-us/products/cpap/machines/airmini/
  3. ResMed. AirMini app Patient eHelp (iOS, 2281192/3): pairing, Test Drive, Mask Fit, comfort settings, score, firmware. https://document.resmed.com/documents/products/machine/airmini/patient-ehelp/airmini_patient-ehelp-ios_amer_eng.pdf
  4. Patil SP, et al. Treatment of Adult Obstructive Sleep Apnea With Positive Airway Pressure: an AASM systematic review, meta-analysis, and GRADE assessment. J Clin Sleep Med. 2019. https://pubmed.ncbi.nlm.nih.gov/30736888/
  5. ResMed knowledge base. Does AirMini have a humidifier? (HumidX performance). https://ap.resmed.com/knowledge/does-airmini-have-a-humidifier
  6. Martins De Araujo MT, et al. Heated humidification or face mask to prevent upper airway dryness during continuous positive airway pressure therapy. Chest. 2000. https://pubmed.ncbi.nlm.nih.gov/10631212/
  7. ResMed knowledge base. Does the patient need the app to use the AirMini? https://ap.resmed.com/knowledge/does-the-patient-need-the-app-to-use-the-airmini
  8. ResMed knowledge base. How many smartphones can be paired with an individual AirMini? https://ap.resmed.com/knowledge/how-many-smartphones-can-be-paired-with-an-individual-airmini
  9. ResMed knowledge base. How close must the smartphone be to the AirMini for the app to work? https://ap.resmed.com/knowledge/how-close-must-the-smartphone-be-to-the-airmini-for-the-app-to-work
  10. Budhiraja R, et al. Early CPAP use identifies subsequent adherence to CPAP therapy. Sleep. 2007. https://pubmed.ncbi.nlm.nih.gov/17425228/
  11. ResMed knowledge base. How do I access Clinical Mode from the patient screen? (gesture and confirmation light). https://ap.resmed.com/knowledge/how-do-i-access-clinical-mode-from-the-patient-screen
  12. ResMed knowledge base. How do I change the AirMini prescription settings? (home-page gesture and Exit). https://ap.resmed.com/knowledge/how-do-i-change-the-airmini-prescription-settings
  13. ResMed knowledge base. How much louder is AirMini compared to an AirSense 10? https://ap.resmed.com/knowledge/how-much-louder-is-airmini-compared-to-an-airsense-10
  14. ResMed knowledge base. How does the AirMini motor compare to the AirSense 10? https://ap.resmed.com/knowledge/how-does-the-airmini-motor-compare-to-airsense10
  15. ResMed knowledge base. Can the AirMini app inform the patient when to replace supplies? https://ap.resmed.com/knowledge/can-the-airmini-app-inform-the-patient-when-to-replace-supplies
  16. ResMed. Travel Compliance Letter for ResMed Therapy Devices (March 17, 2026). https://document.resmed.com/documents/articles/travel-compliance-letter_amer_eng.pdf
  17. ResMed knowledge base. How does the patient turn airplane mode on or off? https://ap.resmed.com/knowledge/how-does-the-patient-turn-airplane-mode-on-or-off
  18. ResMed knowledge base. How can I travel with my CPAP machine? https://ap.resmed.com/knowledge/how-can-i-travel-with-my-cpap-machine
  19. Electronic Code of Federal Regulations. 14 CFR 382.121, assistive devices in the aircraft cabin. https://www.ecfr.gov/current/title-14/chapter-II/subchapter-D/part-382/subpart-I/section-382.121
  20. Transportation Security Administration. Nebulizers, CPAPs, BiPAPs, and APAPs. https://www.tsa.gov/travel/security-screening/whatcanibring/items/nebulizers-cpaps-bipaps-and-apaps
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About the Author
Oluwaseun Adeola

Oluwaseun Adeola

Sleep Health Writer

Oluwaseun Adeola is a sleep health writer at Sleeplay, focused on CPAP therapy and sleep apnea solutions. He reviews machines, masks, and travel gear, turning complex details into clear, practical guidance. His work helps readers choose with confidence, improve comfort, and ultimately sleep better and live better.
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Aliria Perez, CRT

Aliria Perez, CRT

Certified Respiratory Therapist

Certified Respiratory Therapist (CRT, credentialed by the NBRC) with experience in respiratory care, specializing in sleep apnea education and patient-centered therapy. Extensive background working with Durable Medical Equipment (DME) providers and clinical teams to support patients with the setup and use of CPAP, BiPAP, and other positive airway pressure (PAP) devices.I’ve conducted high-volume in-home and virtual consultations, educating patients on the causes and impact of sleep apnea, available treatment options, and the clinical benefits of consistent therapy use. My focus is on improving patient understanding, driving adherence, and helping individuals achieve better long-term sleep and respiratory health.

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